# Anne Bertolotti

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Anne Bertolotti Part 3: A Platform to Identify Selective Protein Phosphatase Inhibitors

Bertolotti describes a platform developed by her lab that has allowed them to rationally identify selective protein phosphatase inhibitors. Using this platform her lab identified a novel small molecule phosphatase inhibitor that blocks the accumulation of misfolded proteins in the cytosol or nucleu…

Anne Bertolotti Part 3: A Platform to Identify Selective Protein Phosphatase Inhibitors

Bertolotti describes a platform developed by her lab that has allowed them to rationally identify selective protein phosphatase inhibitors. Using this platform her lab identified a novel small molecule phosphatase inhibitor that blocks the accumulation of misfolded proteins in the cytosol or nucleu…

Anne Bertolotti (MRC LMB) 2: Benefits of Phosphatase Inhibition for Neurodegenerative Diseases

https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neu…

Anne Bertolotti (MRC LMB) 1: A Historical Perspective on Protein Phosphatases (Audio-Only version)

Audio-Only version https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulat…

Anne Bertolotti (MRC LMB) 3: A Platform to Identify Selective Protein Phosphatase Inhibitors

https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neu…

Anne Bertolotti (MRC LMB) 3: A Platform to Identify Selective Protein Phosphatase Inhibitors (with English subtitles)

https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neu…

Anne Bertolotti (MRC LMB) 2: Benefits of Phosphatase Inhibition for Neurodegenerative Diseases (with English subtitles)

https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neu…

Anne Bertolotti (MRC LMB) 1: A Historical Perspective on Protein Phosphatases (with English subtitles)

https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neu…

Anne Bertolotti (MRC LMB) 3: A Platform to Identify Selective Protein Phosphatase Inhibitors (Audio-Only version)

Audio-Only version https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulat…

Anne Bertolotti (MRC LMB) 2: Benefits of Phosphatase Inhibition for Neurodegenerative Diseases (Audio-Only version)

Audio-Only version https://www.ibiology.org/cell-biology/protein-phosphatases Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulat…